Evidence Insight
chembl-database
Query the ChEMBL database for bioactive molecules, targets, bioactivities, and approved drugs; use this when you need to filter by physicochemical properties (e.g., MW, LogP), chemical structure (SMILES), or retrieve drug mechanism information.
89100Total Score
Core Capability
83 / 100
Functional Suitability
10 / 12
Reliability
9 / 12
Performance & Context
8 / 8
Agent Usability
13 / 16
Human Usability
8 / 8
Security
9 / 12
Maintainability
10 / 12
Agent-Specific
16 / 20
Medical Task
20 / 20 Passed
97Find candidate compounds by name or synonym (e.g., searching for “aspirin”) and retrieve their ChEMBL records
4/4
93Filter molecules by physicochemical properties (e.g., molecular weight, LogP) to narrow down drug-like candidates
4/4
91Molecule search by preferred name and other metadata fields
4/4
91Property-based filtering (e.g., MW, LogP) using ChEMBL API filter syntax
4/4
91End-to-end case for Molecule search by preferred name and other metadata fields
4/4
Veto GatesRequired pass for any deployment consideration
Skill Veto✓ All 4 gates passed
✓
Operational Stability
System remains stable across varied inputs and edge cases
PASS✓
Structural Consistency
Output structure conforms to expected skill contract format
PASS✓
Result Determinism
Equivalent inputs produce semantically equivalent outputs
PASS✓
System Security
No prompt injection, data leakage, or unsafe tool use detected
PASSResearch Veto✅ PASS — Applicable
| Dimension | Result | Detail |
|---|---|---|
| Scientific Integrity | PASS | The legacy audit did not indicate that retrieval outputs were presented as unsupported findings. |
| Practice Boundaries | PASS | The package stayed in retrieval, extraction, or evidence-organization scope rather than drifting into unsupported interpretation. |
| Methodological Ground | PASS | The legacy audit preserved a method-grounded interpretation of the Query the ChEMBL database for bioactive molecules, targets, bioactivities, and approved drugs; use this when you need to filter by physicochemical properties (e.g., MW, LogP), chemical structure (SMILES), or retrieve drug mechanism information workflow. |
| Code Usability | PASS | Code usability passed because the search or lookup workflow still exposed a usable entrypoint and output expectation. |
Core Capability83 / 100 — 8 Categories
Functional Suitability
The archived deduction in functional suitability traces back to: Improve stress-case output rigor. Stress and boundary scenarios show weaker consistency
10 / 12
83%
Reliability
The archived deduction in reliability traces back to: Improve stress-case output rigor. Stress and boundary scenarios show weaker consistency
9 / 12
75%
Performance & Context
The legacy audit gave full marks to performance context for this package.
8 / 8
100%
Agent Usability
The legacy audit deducted points for chembl-database in agent usability.
13 / 16
81%
Human Usability
The legacy audit gave full marks to human usability for this package.
8 / 8
100%
Security
A modest deduction remained in security for chembl-database in the archived review.
9 / 12
75%
Maintainability
A modest deduction remained in maintainability for chembl-database in the archived review.
10 / 12
83%
Agent-Specific
The archived deduction in agent specific traces back to: Improve stress-case output rigor. Stress and boundary scenarios show weaker consistency
16 / 20
80%
Core Capability Total83 / 100
Medical TaskExecution Average: 92.6 / 100 — Assertions: 20/20 Passed
97
Canonical
Find candidate compounds by name or synonym (e.g., searching for “aspirin”) and retrieve their ChEMBL records
4/4 ✓
93
Variant A
Filter molecules by physicochemical properties (e.g., molecular weight, LogP) to narrow down drug-like candidates
4/4 ✓
91
Edge
Molecule search by preferred name and other metadata fields
4/4 ✓
91
Variant B
Property-based filtering (e.g., MW, LogP) using ChEMBL API filter syntax
4/4 ✓
91
Stress
End-to-end case for Molecule search by preferred name and other metadata fields
4/4 ✓
97
Canonical✅ Pass
Find candidate compounds by name or synonym (e.g., searching for “aspirin”) and retrieve their ChEMBL records
This canonical case stayed inside the documented workflow and remained instruction-led.
Basic 36/40|Specialized 60/60|Total 97/100
✅A1The chembl-database output structure matches the documented deliverable
✅A2The instruction path remains actionable for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
93
Variant A✅ Pass
Filter molecules by physicochemical properties (e.g., molecular weight, LogP) to narrow down drug-like candidates
This variant a case stayed inside the documented workflow and remained instruction-led.
Basic 34/40|Specialized 59/60|Total 93/100
✅A1The chembl-database output structure matches the documented deliverable
✅A2The instruction path remains actionable for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
91
Edge✅ Pass
Molecule search by preferred name and other metadata fields
This edge case stayed inside the documented workflow and remained instruction-led.
Basic 33/40|Specialized 58/60|Total 91/100
✅A1The chembl-database output structure matches the documented deliverable
✅A2The instruction path remains actionable for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
91
Variant B✅ Pass
Property-based filtering (e.g., MW, LogP) using ChEMBL API filter syntax
The archived run for Property-based filtering (e.g., MW, LogP) using ChEMBL API filter syntax remained guidance-driven rather than command-driven.
Basic 32/40|Specialized 59/60|Total 91/100
✅A1The chembl-database output structure matches the documented deliverable
✅A2The instruction path remains actionable for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
91
Stress✅ Pass
End-to-end case for Molecule search by preferred name and other metadata fields
The archived run for End-to-end case for Molecule search by preferred name and other... remained guidance-driven rather than command-driven.
Basic 29/40|Specialized 60/60|Total 91/100
✅A1The chembl-database output structure matches the documented deliverable
✅A2The instruction path remains actionable for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
Medical Task Total92.6 / 100
Key Strengths
- Primary routing is Evidence Insight with execution mode B
- Static quality score is 83/100 and dynamic average is 79.6/100
- Assertions and command execution outcomes are recorded per input for human review
- Execution verification summary: Script verification 1/1; adjustment=5. query_chembl.py: OK