Evidence Insight
reactome-skill
92100Total Score
Core Capability
85 / 100
Functional Suitability
11 / 12
Reliability
9 / 12
Performance & Context
8 / 8
Agent Usability
14 / 16
Human Usability
8 / 8
Security
9 / 12
Maintainability
9 / 12
Agent-Specific
17 / 20
Medical Task
20 / 20 Passed
100You have a list of genes/proteins and want to run pathway overrepresentation (enrichment) analysis against Reactome
4/4
97You need to retrieve curated pathway content (hierarchy, reactions, participants) by Reactome stable IDs (e.g., R-HSA-69278)
4/4
95Pathway enrichment (overrepresentation) for identifier lists
4/4
94Expression analysis by mapping expression data to Reactome pathways
4/4
94End-to-end case for Pathway enrichment (overrepresentation) for identifier lists
4/4
Veto GatesRequired pass for any deployment consideration
Skill Veto✓ All 4 gates passed
✓
Operational Stability
System remains stable across varied inputs and edge cases
PASS✓
Structural Consistency
Output structure conforms to expected skill contract format
PASS✓
Result Determinism
Equivalent inputs produce semantically equivalent outputs
PASS✓
System Security
No prompt injection, data leakage, or unsafe tool use detected
PASSResearch Veto✅ PASS — Applicable
| Dimension | Result | Detail |
|---|---|---|
| Scientific Integrity | PASS | Scientific content remained anchored to fetched metadata or source-linked evidence in the legacy review. |
| Practice Boundaries | PASS | Practice boundaries held because the package remained focused on source handling, lookup, or structured evidence use. |
| Methodological Ground | PASS | No methodological-grounding issue was recorded for reactome-skill in the archived evaluation. |
| Code Usability | PASS | Code usability passed because the search or lookup workflow still exposed a usable entrypoint and output expectation. |
Core Capability85 / 100 — 8 Categories
Functional Suitability
A modest deduction remained in functional suitability for reactome-skill in the archived review.
11 / 12
92%
Reliability
The archived evaluation left some headroom for reactome-skill under reliability.
9 / 12
75%
Performance & Context
No point loss was recorded for performance context in the legacy audit.
8 / 8
100%
Agent Usability
The archived evaluation left some headroom for reactome-skill under agent usability.
14 / 16
88%
Human Usability
No point loss was recorded for human usability in the legacy audit.
8 / 8
100%
Security
The archived evaluation left some headroom for reactome-skill under security.
9 / 12
75%
Maintainability
A modest deduction remained in maintainability for reactome-skill in the archived review.
9 / 12
75%
Agent-Specific
The archived evaluation left some headroom for reactome-skill under agent specific.
17 / 20
85%
Core Capability Total85 / 100
Medical TaskExecution Average: 96 / 100 — Assertions: 20/20 Passed
100
Canonical
You have a list of genes/proteins and want to run pathway overrepresentation (enrichment) analysis against Reactome
4/4 ✓
97
Variant A
You need to retrieve curated pathway content (hierarchy, reactions, participants) by Reactome stable IDs (e.g., R-HSA-69278)
4/4 ✓
95
Edge
Pathway enrichment (overrepresentation) for identifier lists
4/4 ✓
94
Variant B
Expression analysis by mapping expression data to Reactome pathways
4/4 ✓
94
Stress
End-to-end case for Pathway enrichment (overrepresentation) for identifier lists
4/4 ✓
100
Canonical✅ Pass
You have a list of genes/proteins and want to run pathway overrepresentation (enrichment) analysis against Reactome
The You have a list of genes/proteins and want to run pathway... scenario completed within the documented Query the Reactome REST API for pathway content and enrichment analyses boundary.
Basic 38/40|Specialized 60/60|Total 100/100
✅A1The reactome-skill output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
97
Variant A✅ Pass
You need to retrieve curated pathway content (hierarchy, reactions, participants) by Reactome stable IDs (e.g., R-HSA-69278)
The You need to retrieve curated pathway content (hierarchy, reactions,... scenario completed within the documented Query the Reactome REST API for pathway content and enrichment analyses boundary.
Basic 36/40|Specialized 60/60|Total 97/100
✅A1The reactome-skill output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
95
Edge✅ Pass
Pathway enrichment (overrepresentation) for identifier lists
The archived evaluation treated Pathway enrichment (overrepresentation) for identifier lists as a clean in-scope run.
Basic 35/40|Specialized 60/60|Total 95/100
✅A1The reactome-skill output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
94
Variant B✅ Pass
Expression analysis by mapping expression data to Reactome pathways
The archived evaluation treated Expression analysis by mapping expression data to Reactome pathways as a clean in-scope run.
Basic 34/40|Specialized 60/60|Total 94/100
✅A1The reactome-skill output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
94
Stress✅ Pass
End-to-end case for Pathway enrichment (overrepresentation) for identifier lists
The End-to-end case for Pathway enrichment (overrepresentation) for... scenario completed within the documented Query the Reactome REST API for pathway content and enrichment analyses boundary.
Basic 31/40|Specialized 60/60|Total 94/100
✅A1The reactome-skill output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
Medical Task Total96 / 100
Key Strengths
- Primary routing is Evidence Insight with execution mode B
- Static quality score is 85/100 and dynamic average is 83.6/100
- Assertions and command execution outcomes are recorded per input for human review
- Execution verification summary: Script verification 1/1; adjustment=5. reactome_tool.py: OK