Evidence Insight
clinvar-database
92100Total Score
Core Capability
85 / 100
Functional Suitability
11 / 12
Reliability
9 / 12
Performance & Context
8 / 8
Agent Usability
14 / 16
Human Usability
8 / 8
Security
9 / 12
Maintainability
9 / 12
Agent-Specific
17 / 20
Medical Task
20 / 20 Passed
100You need to find ClinVar variant records by gene, condition/phenotype, or clinical significance (e.g., *BRCA1* + *pathogenic*)
4/4
97You want to interpret a variant’s clinical significance (Pathogenic/Benign/VUS) and review status for reporting or triage
4/4
95ClinVar search via NCBI E-utilities using flexible query terms (gene/condition/significance)
4/4
94Clinical interpretation retrieval, including clinical significance categories and review status
4/4
94End-to-end case for ClinVar search via NCBI E-utilities using flexible query terms (gene/condition/significance)
4/4
Veto GatesRequired pass for any deployment consideration
Skill Veto✓ All 4 gates passed
✓
Operational Stability
System remains stable across varied inputs and edge cases
PASS✓
Structural Consistency
Output structure conforms to expected skill contract format
PASS✓
Result Determinism
Equivalent inputs produce semantically equivalent outputs
PASS✓
System Security
No prompt injection, data leakage, or unsafe tool use detected
PASSResearch Veto✅ PASS — Applicable
| Dimension | Result | Detail |
|---|---|---|
| Scientific Integrity | PASS | The legacy audit did not indicate that retrieval outputs were presented as unsupported findings. |
| Practice Boundaries | PASS | The legacy review kept this workflow on the evidence-access side of the boundary, not the advice-giving side. |
| Methodological Ground | PASS | No methodological-grounding issue was recorded for clinvar-database in the archived evaluation. |
| Code Usability | PASS | Code usability passed because the search or lookup workflow still exposed a usable entrypoint and output expectation. |
Core Capability85 / 100 — 8 Categories
Functional Suitability
A modest deduction remained in functional suitability for clinvar-database in the archived review.
11 / 12
92%
Reliability
A modest deduction remained in reliability for clinvar-database in the archived review.
9 / 12
75%
Performance & Context
The legacy audit gave full marks to performance context for this package.
8 / 8
100%
Agent Usability
The legacy audit deducted points for clinvar-database in agent usability.
14 / 16
88%
Human Usability
No point loss was recorded for human usability in the legacy audit.
8 / 8
100%
Security
A modest deduction remained in security for clinvar-database in the archived review.
9 / 12
75%
Maintainability
A modest deduction remained in maintainability for clinvar-database in the archived review.
9 / 12
75%
Agent-Specific
The legacy audit deducted points for clinvar-database in agent specific.
17 / 20
85%
Core Capability Total85 / 100
Medical TaskExecution Average: 96 / 100 — Assertions: 20/20 Passed
100
Canonical
You need to find ClinVar variant records by gene, condition/phenotype, or clinical significance (e.g., *BRCA1* + *pathogenic*)
4/4 ✓
97
Variant A
You want to interpret a variant’s clinical significance (Pathogenic/Benign/VUS) and review status for reporting or triage
4/4 ✓
95
Edge
ClinVar search via NCBI E-utilities using flexible query terms (gene/condition/significance)
4/4 ✓
94
Variant B
Clinical interpretation retrieval, including clinical significance categories and review status
4/4 ✓
94
Stress
End-to-end case for ClinVar search via NCBI E-utilities using flexible query terms (gene/condition/significance)
4/4 ✓
100
Canonical✅ Pass
You need to find ClinVar variant records by gene, condition/phenotype, or clinical significance (e.g., *BRCA1* + *pathogenic*)
You need to find ClinVar variant records by gene,... remained well-aligned with the documented contract in the preserved audit.
Basic 38/40|Specialized 60/60|Total 100/100
✅A1The clinvar-database output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
97
Variant A✅ Pass
You want to interpret a variant’s clinical significance (Pathogenic/Benign/VUS) and review status for reporting or triage
The You want to interpret a variant’s clinical significance... scenario completed within the documented Utilities for querying the NCBI ClinVar database to retrieve variant records, clinical... boundary.
Basic 36/40|Specialized 60/60|Total 97/100
✅A1The clinvar-database output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
95
Edge✅ Pass
ClinVar search via NCBI E-utilities using flexible query terms (gene/condition/significance)
The ClinVar search via NCBI E-utilities using flexible query terms... scenario completed within the documented Utilities for querying the NCBI ClinVar database to retrieve variant records, clinical... boundary.
Basic 35/40|Specialized 60/60|Total 95/100
✅A1The clinvar-database output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
94
Variant B✅ Pass
Clinical interpretation retrieval, including clinical significance categories and review status
The archived evaluation treated Clinical interpretation retrieval, including clinical significance... as a clean in-scope run.
Basic 34/40|Specialized 60/60|Total 94/100
✅A1The clinvar-database output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
94
Stress✅ Pass
End-to-end case for ClinVar search via NCBI E-utilities using flexible query terms (gene/condition/significance)
The End-to-end case for ClinVar search via NCBI E-utilities using... scenario completed within the documented Utilities for querying the NCBI ClinVar database to retrieve variant records, clinical... boundary.
Basic 31/40|Specialized 60/60|Total 94/100
✅A1The clinvar-database output structure matches the documented deliverable
✅A2The script execution path completed successfully for the documented case
✅A3The output stays fully within the documented skill boundary
✅A4The response quality is acceptable for the documented path
Pass rate: 4 / 4
Medical Task Total96 / 100
Key Strengths
- Primary routing is Evidence Insight with execution mode B
- Static quality score is 85/100 and dynamic average is 83.6/100
- Assertions and command execution outcomes are recorded per input for human review
- Execution verification summary: Script verification 2/2; adjustment=5. annotate.py: OK; search.py: OK