Research Proposal Generator
Generates a comprehensive research proposal design based on input literature, including hypothesis, mechanism verification, and budget.
SKILL.md
Research Proposal Generator
This skill analyzes a given literature text (paper) and generates a complete research proposal design, including scientific hypothesis, research outline, detailed experimental design, budget, and yearly plan.
When to Use
- Use this skill when the request matches its documented task boundary.
- Use it when the user can provide the required inputs and expects a structured deliverable.
- Prefer this skill for repeatable, checklist-driven execution rather than open-ended brainstorming.
Key Features
- Scope-focused workflow aligned to: Generates a comprehensive research proposal design based on input literature, including hypothesis, mechanism verification, and budget. Use when the user wants to design a research project from a paper.
- Documentation-first workflow with no packaged script requirement.
- Reference material available in
references/for task-specific guidance. - Structured execution path designed to keep outputs consistent and reviewable.
Dependencies
Python:3.10+. Repository baseline for current packaged skills.Third-party packages:not explicitly version-pinned in this skill package. Add pinned versions if this skill needs stricter environment control.
Example Usage
See ## Usage above for related details.
Skill directory: 20260316/scientific-skills/Protocol Design/research-proposal-generator
No packaged executable script was detected.
Use the documented workflow in SKILL.md together with the references/assets in this folder.
Example run plan:
- Read the skill instructions and collect the required inputs.
- Follow the documented workflow exactly.
- Use packaged references/assets from this folder when the task needs templates or rules.
- Return a structured result tied to the requested deliverable.
Implementation Details
- Execution model: validate the request, choose the packaged workflow, and produce a bounded deliverable.
- Input controls: confirm the source files, scope limits, output format, and acceptance criteria before running any script.
- Primary implementation surface: instruction-only workflow in
SKILL.md. - Reference guidance:
references/contains supporting rules, prompts, or checklists. - Parameters to clarify first: input path, output path, scope filters, thresholds, and any domain-specific constraints.
- Output discipline: keep results reproducible, identify assumptions explicitly, and avoid undocumented side effects.
Usage
Input: The text content of a scientific paper.
Output: A structured research proposal in Markdown format.
Procedure
Please follow these steps to generate the proposal. Refer to prompts.md for detailed prompts for each step.
Step 1: Analysis & Extraction
- Extract Hypothesis: Analyze the input text to extract the scientific hypothesis and cell phenotype.
- Extract Key Info: Extract molecular mechanisms, signaling pathways, and regulatory relationships. Identify the "Start Variable" (first gene in results).
- Extract Clinical Info: Extract clinical questions and their relation to the hypothesis.
Step 2: Outline Generation
- Generate Outline: Based on the Hypothesis, Key Info, and Clinical Info, generate a research proposal outline (Section 2. Research Plan).
- Constraint: The outline should start from bioinformatic screening to mechanism verification.
Step 3: Detailed Experimental Design
- Identify Molecules: Scan the outline to identify key genes/molecules.
- Design Experiments: For each section of the outline, design detailed experiments.
- Requirement: Include Model, Groups, Sample, Method, Index, Expected Results.
- Rule: Each part usually studies relationship between two variables.
- Rule: Animal experiments must start with modeling.
- Reference: Use the "Design Experiments" prompt in
references/prompts.md.
Step 4: Final Compilation
- Generate Overview: Write Section "1. Overview" (Disease introduction) based on the hypothesis.
- Generate Budget: Create a budget explanation (Section "3. Budget") for a 3-year plan (RMB).
- Generate Yearly Plan: Create a 3-year research schedule (Section "4. Yearly Plan").
Step 5: Output Assembly
Assemble the final report in the following order:
- 1. Overview
- 2. Research Plan (With detailed experiments inserted)
- 3. Budget
- 4. Yearly Plan
Note: This process simulates a multi-step expert workflow. Ensure consistency between the hypothesis and the designed experiments.
When Not to Use
- Do not use this skill when the required source data, identifiers, files, or credentials are missing.
- Do not use this skill when the user asks for fabricated results, unsupported claims, or out-of-scope conclusions.
- Do not use this skill when a simpler direct answer is more appropriate than the documented workflow.
Required Inputs
- A clearly specified task goal aligned with the documented scope.
- All required files, identifiers, parameters, or environment variables before execution.
- Any domain constraints, formatting requirements, and expected output destination if applicable.
Recommended Workflow
- Validate the request against the skill boundary and confirm all required inputs are present.
- Select the documented execution path and prefer the simplest supported command or procedure.
- Produce the expected output using the documented file format, schema, or narrative structure.
- Run a final validation pass for completeness, consistency, and safety before returning the result.
Output Contract
- Return a structured deliverable that is directly usable without reformatting.
- If a file is produced, prefer a deterministic output name such as
research_proposal_generator_result.mdunless the skill documentation defines a better convention. - Include a short validation summary describing what was checked, what assumptions were made, and any remaining limitations.
Validation and Safety Rules
- Validate required inputs before execution and stop early when mandatory fields or files are missing.
- Do not fabricate measurements, references, findings, or conclusions that are not supported by the provided source material.
- Emit a clear warning when credentials, privacy constraints, safety boundaries, or unsupported requests affect the result.
- Keep the output safe, reproducible, and within the documented scope at all times.
Failure Handling
- If validation fails, explain the exact missing field, file, or parameter and show the minimum fix required.
- If an external dependency or script fails, surface the command path, likely cause, and the next recovery step.
- If partial output is returned, label it clearly and identify which checks could not be completed.
Quick Validation
Run this minimal verification path before full execution when possible:
No local script validation step is required for this skill.
Expected output format:
Result file: research_proposal_generator_result.md
Validation summary: PASS/FAIL with brief notes
Assumptions: explicit list if any